What is the metabolic role of phosphoenolpyruvate carboxykinase?
نویسندگان
چکیده
Published, JBC Papers in Press, July 27, 2009, DOI 10.1074/jbc.R109.040543 Jianqi Yang, Satish C. Kalhan, and Richard W. Hanson From the Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-4936 and the Departments of Pathobiology and Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, Ohio 44195
منابع مشابه
Glucokinase and cytosolic phosphoenolpyruvate carboxykinase (GTP) in the human liver. Regulation of gene expression in cultured hepatocytes.
Glucokinase and phosphoenolpyruvate carboxykinase are key enzymes of glucose metabolism in the rat liver. The former is considered to be instrumental in regulating glucose hepatic release/uptake according to the glycaemia level, and cytosolic phosphoenolpyruvate carboxykinase is a major flux-generating enzyme for gluconeogenesis. The level of expression of both enzymes and the regulation of the...
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 284 40 شماره
صفحات -
تاریخ انتشار 2009